Cannabidiols and opioids share several interdependent, but not identical, medical properties that indicate using them together can be far more effective than using traditional opioids on their own. In one study, there was a decrease in pain level by 27% when patients were introduced to a CBD-opioid combination treatment, as measured against the use of opioids on their own.(4)
CBD is effective because it works within the spinal cord system of nerve endings, called glycine receptors. Several recent clinical studies have demonstrated that CBD can be an effective therapeutic option for patients with neuropathic pain and other types of chronic pain. Recent studies have shown that glycine receptors (GlyRs) are an important target for cannabinoids in the central nervous system.(5)
Because these glycine receptors have far-reaching impact on a number of body functions, finding an alternative treatment that is safe and effective in utilizing their properties is a breakthrough in pain management that has come about in the last decade.
In promising research, CBD and other cannabinoids have been shown to have analgesic properties for terminal cancer patients who have developed a strong resistance to opioid analgesics. This research indicates that in the case of patients whose bodies have become accustomed to high doses of traditional painkillers, CBD can provide a safe and effective alternative treatment.